Organizing Centres

Blandine Bruneel, CRCL, UMR Inserm 1052 CNRS 5286, Lyon, France
Christophe Caux, CRCL, UMR Inserm 1052 CNRS 5286, Lyon, France
Thierry Defrance, CIRI, UMR Inserm 1111, CNRS 5308, Lyon, France
Marlène Dreux, CIRI, UMR Inserm 1111, CNRS 5308, Lyon, France
Hélène Dutartre, CIRI, UMR Inserm 1111, CNRS 5308, Lyon, France
Janet Hall, CRCL, UMR Inserm 1052 CNRS 5286, Lyon, France
Julien Marie, CRCL, UMR Inserm 1052 CNRS 5286, Lyon, France
Anne Sophie Michallet, CIRI, UMR Inserm 1111, CNRS 5308, Lyon, France
Virginie Petrilli, CRCL, UMR Inserm 1052 CNRS 5286, Lyon, France
Jenny Valladeau, CRCL, UMR Inserm 1052 CNRS 5286, Lyon, France
Thierry Walzer, CIRI, UMR Inserm 1111, CNRS 5308, Lyon, France

The International Center for Infectiology Research (CIRI) was created on 1st January 2013 through collaboration between Inserm, CNRS, ENS Lyon and Claude Bernard Lyon 1 University. Together with these trustees and its other partners, including Institut Pasteur, the Mérieux Foundation and the Lyon Civil Hospitals (HCL), the CIRI hosts over 20 scientific teams with one joint goal: the fight against infectious diseases, the second cause of death worldwide. Through a multidisciplinary approach combining microbiology (bacteriology and virology), immunology, cell biology, clinical research and epidemiology, and with a strong interface with the industry, the CIRI’s objective is to be a research center developing therapeutic innovations and to act as a major player in the areas of medical prevention and treatment of infectious diseases. 300 researchers, faculty members, graduate students, engineers and technicians are based at the CIRI with a strong expertise in key basic disciplines essential for the study of infectious diseases (i.e., microbiology, immunology and cell biology) and a capacity and specific interest to translate novel knowledge of scientific or technological nature into translational research programs and applied research. This joint research Unit (INSERM U1111 – CNRS UMR5308 – ENS Lyon – UCB Lyon 1) is directed by Dr François-Loïc Cosset and his deputy Professor François Vandenesch. The research programs of CIRI cover the major research areas of infectious diseases: Integrated immunology for vaccination and biotherapies. Metabolo-infectiology and non-communicable diseases. Nosocomial infections. Emerging and highly pathogenic infections. Consequences of co-infections with human pathogenic agents. CIRI Website: http://ciri.inserm.fr/

 

The Cancer Research Centre of Lyon (CRCL, UMR Inserm 1052 CNRS 5286 Centre Léon Bérard, Direction Professor Alain Puisieux, Deputies Dr Patrick Mehlen and Pr Charles Dumontet) is a research structure created in January 2011 affiliated to the Claude Bernard Lyon 1 University, Inserm, CNRS and the regional Léon Bérard Cancer Centre (CLB) and has a partnership with the HCL. The CRCL’s objectives are to create a centre of excellence in tumor biology in Lyon and participate in education and training in oncology. An important asset of the CRCL is the strong links established with clinical departments from the CLB and the HCL, fostering the transfer from basic research to medical applications. Currently, the CRCL is composed of 21 teams, organized into three scientific departments, with a total of 450 staff, including 137 permanent researchers. Research at the CRCL is structured around the notions that tumorigenesis and tumor development depend on the adaptation of cancer cells to and/or their escape mechanisms from biological constraints and onco-suppressive mechanisms they are subjected to. A shared objective is the characterization and validation of innovative therapeutic targets, designed to block the plasticity and adaptability of malignant cells, in order to restore the senescence, apoptosis and immune-surveillance programs. Beyond its own research programs, the CRCL has been a stepping-stone for the development of new structures in Lyon: the DEVweCAN LabEx (Dir. Patrick Mehlen) and the LYRIC (Lyon Integrated Research Institute in Cancer, Dir. Jean-Yves Blay). The creation of these two new structures, linked to both the hospitals and the CRCL, is an important element toward the implantation of a comprehensive cancer center in Lyon. CRCL website: www.crcl.fr